On Wednesday night’s sex and relationship show, a caller asked HLN’s Dr. Drew and his guests why some gay men marry straight women and “ruin their lives?”

Dr. Drew's “Loveline” co-host Simone Bienne responded, “I would say because there's a lot of shame behind it and it's difficult to still come out today in 2012 as a gay man.”

Dr. Drew added, “There are gay homophobic men … and wish they could be otherwise and try to live otherwise, but they are not that, so they can't.”

Hear the clip in its entirety in the video player above.

Watch Dr. Drew Monday through Thursday on HLN at 9 p.m. ET and follow the show on Twitter @DrDrewHLN.